| 中文产品名称 | 重组小鼠成纤维细胞生长因子4(FGF-4) |
| 英文产品名称 | Mouse FGF-4 Protein |
| 产品别名 | HST-1, Transforming protein KS3, HBGF-4 |
| 产品描述 | Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development. |
| 种属 | 小鼠 |
| 表达宿主 | 大肠杆菌 |
| 分子 | FGF-4 |
| 检测指标 | FGF-4 |
| 活性 | Testing in Progress |
| 蛋白长度 | 重组小鼠FGF4蛋白由136个氨基酸组成,预计分子量为15.15 kDa。 |
| 纯度 | > 95 % ,使用SDS-PAGE检测 |
| 产品形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,50 mM NaCl,pH 8.0。 |
| 特点 | 通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。 |
| 分子量 | 15.15 KDa |
| 使用中注意事项 | 开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
| 保存建议 | 本产品为冻干粉形式,建议:将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
| 运输条件 | 冰袋运输(蓝冰) |
| 警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
| 基因ID | 5008 |
| 蛋白质ID | P11403 |